Dually responsive biodegradable drug releasing <scp>3D</scp> printed structures

Ultrasound and pH Dually Responsive Polymer Vesicles for Anticancer Drug Delivery

Recently, smart polymer vesicles have attracted increasing interest due to their endless potential applications such as tunable delivery vehicles for the treatment of degenerative diseases. However, the evolution of stimuli-responsive vesicles from bench to bedside still seems far away for the limitations of current stimuli forms such as temperature, light, redox, etc. Since ultrasound combined...

Rapid interferometric imaging of printed drug laden multilayer structures

The developments in printing technologies allow fabrication of micron-size nano-layered delivery systems to personal specifications. In this study we fabricated layered polymer structures for drug-delivery into a microfluidic channel and aimed to interferometrically assure their topography and adherence to each other. We present a scanning white light interferometer (SWLI) method for quantitati...

3D-Printed Biodegradable Polymeric Vascular Grafts.

Congenital heart defect interventions may benefit from the fabrication of patient-specific vascular grafts because of the wide array of anatomies present in children with cardiovascular defects. 3D printing is used to establish a platform for the production of custom vascular grafts, which are biodegradable, mechanically compatible with vascular tissues, and support neotissue formation and growth.

Biodegradable Thermal-Responsive Dual-Imaging Enabled Nanoparticles

Zhiwei Xie1, Parth Jadeja2, Jyothi U. Menon2, Dheeraj Thakore2, Nikhil Pandey2, Jian Yang1*, Kytai T. Nguyen2* 1 Department of Biomedical Engineering, Materials Research Institute, Huck Institutes of Life Sciences, The Pennsylvania State University, University Park, 16802. * Email: [email protected] 2 Department of Bioengineering, The University of Texas at Arlington, Arlington, TX. * Email: knguye...

Drug-eluting/biodegradable stents.